We are inviting submissions to a new special issue “Scaling, Spatio-Temporal Modeling, and Crisis Informatics” by the ISPRS International Journal of Geo-Information. Articles being submitted should involve advancement to theories and methods and/or applications integrating spatial and temporal datasets at varying scales for crisis informatics. The articles should leverage existing theories and/or develop new theories of scaling and spatiotemporal modeling while taking advantage of big data theories and technologies to aid with crisis/disaster preparedness, mitigation, recovery, and resilience.